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Table 3 Aspirin plus ticlopidine versus aspirin plus oral anticoagulants after stenting

From: Antiplatelet and anticoagulant therapy in elective percutaneous coronary intervention

   

Primary end point (%)

 
 

Number of

Number of

    

Study

patients studied

patients treated

ASA ticlopidine

ASA coumadin

ASA alone

P value

ISAR [84]

517

626

1.6

6.2

-

0.01

FANTASTIC [85]

473

485

5.7

8.6

-

0.37

STARS [86]

1653

1965

0.5

2.7

3.6

0.001

MATTIS [87]

350

350

5.6

11.0

-

0.07

Hall et al [88]

226

358

0.8

-

3.9

0.1

  1. In the ISAR, STARS, MATTIS and Hall et al studies, the primary end point comprised cardiac death, acute myocardial infarction or repeat target vessel revascularization at 30 days. In the FANTASTIC study, the composite of death, acute myocardial infarction or stent occlusion at 6 weeks was the secondary end point and did not include repeat target revascularization.