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Table 7 Proposed features of clinical trials

From: Use of diffusion and perfusion magnetic resonance imaging as a tool in acute stroke clinical trials

Imaging methods

DWI, PWI, MRA, T2/FLAIR

Selection criteria

Cortical DWI lesion > 5 cm3

 

Diffusion-perfusion mismatch

 

No pre-existing lesions in same vascular

 

territory

Outcome variable

Change in lesion volume, pretreatment to

 

chronic (3 months)

Data analysis

Transformed lesion volume (percentage

 

change, log, cube root)

 

Co-variance analysis on baseline variables:

 

   NIHSS, volume of hypoperfusion, initial

 

   lesion volume

  1. DWI, diffusion weighted imaging; PWI, perfusion weighted imaging; MRA, magnetic resonance angiography; FLAIR, fluid-attenuated inversion recovery; NIHSS, National Institutes of Health Stroke Scales.
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Trials

ISSN: 1745-6215