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Jette 1991 [17]
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1. LVEF < 30% Control n = 10
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Supervised in hospital for 4 weeks a.m. - run 5 min × 3/
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LVEF < 30% group
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ExT n = 8
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Peak VO2 increased by 221 ml/min (P < 0.05)
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| | | |
Peak WL increased by 13 W (P < 0.05)
|
| |
2. LVEF 31–50%
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week at 70–80% max HR calisthenics 30 min cycle 15 min at 70–80% max HR p.m. - walk (graded paths) 30–60 min
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LVEF 31–50% group
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| |
Control n = 10
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Peak VO2 increased by 85 ml/min (P = NS)
|
| |
ExT n = 11
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Peak WL increased by 9 W (P = NS)
|
|
Koch 1992 [15]
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1. ExT n = 12
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40 sessions over 90 days, graded program
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QOL score increased by 52% (P < 0.0001)
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| |
2. Control n = 13
| | |
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Belardinelli 1992 [18]
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1. ExT n = 10
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Supervised 8 week program Cycle at 60% VO2peak × 3/week
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Ex tolerance increased by 45% (P < 0.005)
|
| |
2. Control n = 10
| |
Peak O2 uptake increased by 20% (P < 0.001)
|
|
Kostis 1994 [19]
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1. Placebo n = 6
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12 week program Walk/row/cycle/stair climb 60 min × 3–5/week at 50–60% max HR Cognitive behavioral sessions Diet modification
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Ex tolerance increased by 182 s (P < 0.05)
|
| |
2. Digoxin n = 7
| | |
| |
3. ExT n=7
| | |
|
Kiilavuori 1995 [20]
|
1. ExT n = 8
|
Supervised for 3 months Cycle 30 min × 3/week at 50–60% max VO2
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Ex tolerance increased by 71% at submaximal WL (P = 0.01)
|
| |
2. Control n = 12
| |
High frequency component of HR variability increased by 22–55% during the day
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| | | |
(P = 0.0001)
|
|
Hambrecht 1995 [21]
|
1. ExT n= 12
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Supervised for 3 weeks 10 min × 6/day at 70% max VO2 then home-based until 6 months: cycle 40 min/day at 70% max VO2 walk/calisthenics/ball games 60 min × 2/week
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Peak VO2 increased by 12% (P < 0.001)
|
| |
2. Control n=10
| |
Muscle mitochondria volume density increased (P < 0.05)
|
|
Belardinelli 1995 [22]
|
1. ExT n = 36
|
Supervised in hospital Calisthenics warm up 15 min × 3/week Cycle 40 min × 3/week at 60% max VO2
|
Peak VO2 increased by 12% (P < 0.001)
|
| |
2. Control n = 19
| |
Improved indices of diastolic function
|
|
Hambrecht 1997 [23]
|
1. Ext n = 9
|
Supervised for 3 weeks 10 min × 6/day at 70% max VO2 then home-based until 6 months: cycle 40 min/day at 70% max VO2 walk/calisthenics/ball games 60 min × 2/week
|
Enhanced oxidative enzyme activity and improved
|
| |
2. Control n= 9
| |
mitochondrial size and number of cistae in skeletal muscle biopsies
|
|
Dubach 1997 [24]
|
1. ExT n = 12
|
Supervised for 8 weeks Walk 60 min × 2/day Cycle 40 min × 4/week at 80% max VO2
|
Peak VO2 uptake increased
|
| |
2. Control n = 13
| |
Peak WL increased
|
| | | |
Ex time increased
|
|
Reinhart 1998 [25]
|
n = 25
|
8 week residential program Cycle 40 min at 70–80% maximal exercise capacity × 4/week and walk 2 × 1 h/day
|
Increased maximal cardiac output and peak O2 uptake
|
|
Wielanger 1998,
|
1. ExT n = 41
|
Supervised for 12 weeks 3 × 10 min cycle/walk/ball games 5 min rest Exercise at target heart rate (resting HR + 60% difference between resting and maximum HR)
|
Feelings of being disabled decreased as shown by?
|
|
1999 [26,27]
|
2. Control n = 39
| |
Self-Assessment of General Well-Being (SAGWB)
|
| | | |
Ex time increased by 21.4% (P < 0.0001)
|
| | | |
Anaerobic threshold increased by 12.5% (P < 0.05)
|
| | | |
Peak O2 uptake not significantly changed
|
|
Callaerts-Vegh
|
1. ExT n = 9
|
8 weeks intensive training
|
Peak O2 uptake increased by 30.9%
|
|
1998 [28]
|
2. Control n = 8
| |
Urinary nitrate elimination decreased in controls but unchanged in ExT group
|
|
Willenheimer 1998 [29]
|
1. ExT n = 22
|
Supervised for 16 weeks. Interval training: cycle 60 s at 80% VO2max then 30 s rest week 0–7 15 min × 2/week week 7–16 45 min × 3/week
|
Peak ex WL increased by 7 W (P < 0.01)
|
| |
2. Control n = 27
| | |
|
Belardinelli 1999 [16]
|
1. ExT n = 50
|
Supervised 8 week program Cycle at 60% VO2peak × 3/week Supervised 12 month maintenance program: 2 sessions/week: 20 min stretching exercises; 40 min cycle
|
Peak O2 uptake increased by 18% at 2 months (P < 0.001)
|
| |
2. Control n = 49
| |
Lower mortality (n=9 versus n = 20, RR=0.37; 95% CI, 0.17 to 0.84; P = 0.01)
|
| | | |
Fewer hospital readmissions for heart failure (5 versus 14; RR=0.29; 95% CI,
|
| | | |
0.11 to 0.88; P = 0.02)
|
|
Sturm 1999 [30]
|
n = 26
|
12 weeks of 50% maximal exercise capacity training progressing to 100 min step aerobics/week and 50 min cycle/week
|
Peak O2 uptake increased by 23.3% (P = 0.001
|
| | | |
Peak WL increased by 26% (P = 0.0001)
|
|
Keteyian 1999 [31]
|
1. ExT n = 21
|
Warm up 5 min, cool down 11 min 33 min × 3/week at 60–80% max HR (11 min × 3 ergometers: cycle, row, arm, treadmill) × 24 weeks
|
Peak O2 uptake increased (P < 0.05)
|
| |
2. Control n = 22
| |
Improved chronotropic response to exercise
|
|
Quittan 1999 [32]
|
1. n = 25
|
Aerobics 3 h/week
|
Improved QOL (P = 0.0001), physical role fulfillment (P = 0.001), physical (P = 0.02)
|
| | | |
and social (P = 0.0002) functioning
|
| | | |
Peak O2 uptake and ex time increased (P < 0.01)
|
|
Hambrecht 2000 [33]
|
1. ExT n = 36
|
2 weeks × 10 min cycle 4–6/week followed by 6 months home-based cycle × 20 min at 70% peak O2 uptake
|
NYHA class improved
|
| |
2. Control n = 37
| |
Ex time increased
|
| | | |
LVEF increased from 0.30 to 0.35 (P = 0.003)
|
| | | |
Peak ex TPR decreased (P = 0.003)
|
