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Table 3 Concomitant cardiovascular illnesses and risk factors in the overall population

From: Design of a trial evaluating myocardial cell protection with cariporide, an inhibitor of the transmembrane sodium-hydrogen exchanger: the Guard During Ischemia Against Necrosis (GUARDIAN) trial

   

Cariporide

 

All (n=11 587)

Placebo (n=2909)

20 mg (n=2908)

80 mg (n=2887)

120 mg (n=2883)

Median age (years)

66.0

65

66

66

66

Sex (% male)

69.9

70.0

70.2

69.3

69.9

Smoking status (%)

     

   Current

22.8

23.7

22.1

23.0

22.5

   Ex smoker

44.7

44.6

45.1

44.4

44.6

   MI at study entry (%)

10.4

10.0

11.1

10.4

10.1

History of (%)

     

   Stable angina

24.1

23.8

23.9

23.6

25.0

   Unstable angina

58.8

58.0

59.9

59.4

58.0

   MI

44.5

44.0

45.4

44.6

43.9

   Congestive heart failure

7.7

7.1

8.3

7.4

7.9

   Hypertension

53.1

51.8

53.7

53.3

53.5

   Cerebrovascular disease

6.1

5.4

6.0

6.2

6.7

   Peripheral vascular disease

13.5

12.9

13.9

13.9

13.1

   Cardiac arrhythmia

12.2

11.7

13.0

11.5

12.4

   Hypercholesterolemia

55.0

54.3

55.1

55.9

54.8

   NIDDM

19.7

19.2

20.2

20.5

18.9

   IDDM

7.1

6.1

7.2

7.1

8.0

  1. IDDM, insulin-dependent diabetes mellitus; NIDDM, noninsulin-dependent diabetes mellitus.