| | | |
Cariporide
|
|---|
| |
All (n=11 587)
|
Placebo (n=2909)
|
20 mg (n=2908)
|
80 mg (n=2887)
|
120 mg (n=2883)
|
|---|
|
Median age (years)
|
66.0
|
65
|
66
|
66
|
66
|
|
Sex (% male)
|
69.9
|
70.0
|
70.2
|
69.3
|
69.9
|
|
Smoking status (%)
| | | | | |
|
Current
|
22.8
|
23.7
|
22.1
|
23.0
|
22.5
|
|
Ex smoker
|
44.7
|
44.6
|
45.1
|
44.4
|
44.6
|
|
MI at study entry (%)
|
10.4
|
10.0
|
11.1
|
10.4
|
10.1
|
|
History of (%)
| | | | | |
|
Stable angina
|
24.1
|
23.8
|
23.9
|
23.6
|
25.0
|
|
Unstable angina
|
58.8
|
58.0
|
59.9
|
59.4
|
58.0
|
|
MI
|
44.5
|
44.0
|
45.4
|
44.6
|
43.9
|
|
Congestive heart failure
|
7.7
|
7.1
|
8.3
|
7.4
|
7.9
|
|
Hypertension
|
53.1
|
51.8
|
53.7
|
53.3
|
53.5
|
|
Cerebrovascular disease
|
6.1
|
5.4
|
6.0
|
6.2
|
6.7
|
|
Peripheral vascular disease
|
13.5
|
12.9
|
13.9
|
13.9
|
13.1
|
|
Cardiac arrhythmia
|
12.2
|
11.7
|
13.0
|
11.5
|
12.4
|
|
Hypercholesterolemia
|
55.0
|
54.3
|
55.1
|
55.9
|
54.8
|
|
NIDDM
|
19.7
|
19.2
|
20.2
|
20.5
|
18.9
|
|
IDDM
|
7.1
|
6.1
|
7.2
|
7.1
|
8.0
|
- IDDM, insulin-dependent diabetes mellitus; NIDDM, noninsulin-dependent diabetes mellitus.
