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Table 3 Contraindications alteplase.

From: Ultrasound enhanced prehospital thrombolysis using microbubbles infusion in patients with acute ST elevation myocardial infarction: Rationale and design of the Sonolysis study

• Reduced consciousness

 

• Paralysis

 

• Arterial hypertension (systolic pressure > 180 mmHg)

 

• Known or suspected haemorrhagic diathesis

 

• Possible pregnancy

 

• Any history of stroke

 

• In the past 3 months

 

   ◦ Significant trauma

 

   ◦ Major surgery

 

   ◦ Haemoptysis

 

   ◦ Documented ulcerative gastrointestinal disease

 

   ◦ Manifest or recent severe or dangerous bleeding

 

• Allergy to streptokinase or t-PA

 

• Systolic blood pressure of less than 80 mmHg during more than 5 minutes with clinical symptoms of shock