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Table 1 Summary of response from organisations and charities

From: Reporting of clinical trials: a review of research funders' guidelines

Action Number of organisations (percentage) Number of charities (percentage) Total (percentage)
Contacted 25 115 140
Eligibility    
Eligible 17 (68%) 56 (49%) 73 (52%)
Not eligible 4 (16%) 48 (42%) 52 (37%)
No reply 0 (0%) 11 (9%) 11 (8%)
Issue guidelines but do not fund RCTs 4 (16%) 0 (0%) 4 (3%)
Guidelines (n = 73)    
Guidelines/terms and conditions received 14 (82%) 52 (93%) 66 (90%)
Limited contact 2 (12%) 1 (2%) 3 (4%)
No guidelines 1 (6%) 1 (2%) 2 (3%)
Could not send due to confidentiality 0 (0%) 2 (3%) 2 (3%)
Research funder not checked table of information 3 (18%) 8 (14%) 11 (15%)
Not referred to other guidelines 3 (18%) 14 (25%) 17 (23%)
Referred to other guidelines: 1 14 (82%) 42 (75%) 56 (77%)
Association of Medical Research Charities 0 (0%) 18 (43%) 18 (32%)
Department of Health Research Governance Framework (England) 3 (21%) 15 (36%) 18 (32%)
Medical Research Council 5 (36%) 13 (31%) 18 (32%)
International Conference on Harmonisation (ICH) 10 (71%) 4 (10%) 14 (25%)
Medicines for Human use 6 (43%) 8 (19%) 14 (25%)
Institution 0 (0%) 11 (26%) 11 (20%)
Declaration of Helsinki 7 (50%) 2 (5%) 9 (16%)
CONSORT 6 (43%) 0 (0%) 6 (11%)
Charity specific 0 (0%) 4 (10%) 4 (7%)
National regulations and guidelines 1 (7%) 3 (7%) 4 (7%)
Legal 0 (0%) 4 (10%) 4 (7%)
Wellcome Trust 0 (0%) 3 (7%) 3 (5%)
Reference in guidelines/through contact (n = 73) to:    
Trial registration explicitly 12 (71%) 7 (13%) 19 (26%)
Trial registration implicitly 0 (0%) 29 (52%) 29 (40%)
Protocol adherence/amendment explicitly 12 (71%) 20 (36%) 32 (44%)
Protocol adherence/amendment implicitly 2 (12%) 24 (43%) 26 (36%)
Trial publication explicitly 14 (82%) 35 (63%) 49 (67%)
Trial publication implicitly 1 (6%) 13 (23%) 14 (19%)
Monitoring against guidelines explicitly 11 (65%) 36 (64%) 47 (64%)
Monitoring against guidelines implicitly 1 (6%) 11 (20%) 12 (16%)
Publication of negative studies explicitly 6 (35%) 5 (9%) 11 (15%)
Publication of negative studies implicitly 3 (18%) 24 (43%) 27 (37%)
Publication of negative outcomes explicitly 6 (35%) 5 (9%) 11 (15%)
Publication of negative outcomes implicitly 3 (18%) 24 (43%) 27 (37%)
  1. 1. Each charity/organisation may refer to one or more other guidelines
  2. Limited contact meant that there was initial contact with the organisation/charity to confirm that they did fund clinical trials and the maximum grant available was, but then no further information was forthcoming.
  3. Institution means the guidelines refer to the guidelines issued by the university or other institution were the trial is to be conducted from.
  4. Charity specific means that the charity has specific guidelines for the particular disease/illness but not necessarily good research practice guidelines.
  5. National regulations and guidelines are any other guidelines issued nationally e.g. for the UK, America e.t.c.
  6. Legal guidelines means the guidelines refer to specific legal guidelines for clinical trials or the specific disease/illness being studied.