|
Minimisation criteria
|
Categories
|
|---|
|
Smoker at time of TED diagnosis
|
Yes/No
|
|
Previous Steroid use*
|
Yes/No
|
|
Gender
|
Male/Female
|
|
Disease severity
|
TES < 22/TES ≥ 22
|
|
Study Centre
|
MEH/BEH/WEH/UCLH/MREH
|
|
Disease duration
|
< 6 months/≥ 6 months
|
|
Age
|
< 60 years old/≥ 60 years old
|
|
Disease activity
|
CAS 2–3/4–5/6–7
|
|
Thyroid status on enrolment
|
Hypothyroid/Euthyroid/Hyperthyroid
|
- * Defined as ≥ 20 mg of prednisolone for ≥ 1 month in the previous 6 months
- TES: Total Eye Score; MEH: Moorfields Eye Hospital; BEH: Bristol Eye Hospital; WEH: Western Eye Hospital; UCLH: University College London Hospital; MREH: Manchester Royal Eye Hospital; CAS: Clinical Activity Score.
