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Table 4 Trial timeline

From: Protocol for the combined immunosuppression & radiotherapy in thyroid eye disease (CIRTED) trial: A multi-centre, double-masked, factorial randomised controlled trial

Week

-2

0

1–3

4

5–7

13

20

24

28

36

44

48

Orthoptic assessment

✓

✓

 

✓

 

✓

 

✓

 

✓

 

✓

Clinical assessment

✓

✓

 

✓

 

✓

 

✓

 

✓

 

✓

Blood tests

✓

✓

✓

✓

 

✓

✓

✓

✓

✓

✓

✓

Quality of life questionnaires

✓

    

✓

     

✓

Prednisolone

start

      

stop

    

Azathioprine/Placebo

 

start

          

Radiotherapy/Sham-radiotherapy

    

✓

       
  1. Week -2 = enrolment; Week 0 = randomisation