From: Application and investigation of a bound for outcome reporting bias
Odds ratio | Sample size variability parameter | Mean trial size | n | m | True bias: median1 | Difference between unsuppressed pooled and C&J-adjusted: median (2.5th, 97.5th) centiles | Difference between unsuppressed pooled and maximum imputation-adjusted: median (2.5th, 97.5th) centiles |
---|---|---|---|---|---|---|---|
1 | 0.05 | 25 | 4 | 1 | 0.175 | -0.059 (-0.170, 0.117) | -0.142 (-0.334, 0.016) |
1 | 0.05 | 25 | 3 | 2 | 0.345 | -0.087 (-0.293, 0.228) | -0.323 (-0.653, -0.053) |
1 | 0.05 | 300 | 4 | 1 | 0.052 | -0.014 (-0.048, 0.043) | Â |
1 | 0.05 | 300 | 3 | 2 | 0.101 | -0.021 (-0.084, 0.071) | Â |
1 | 0.35 | 25 | 4 | 1 | 0.159 | -0.055 (-0.161, 0.121) | -0.146 (-0.371, 0.030) |
1 | 0.35 | 25 | 3 | 2 | 0.317 | -0.079 (-0.277, 0.220) | -0.310 (-0.661, -0.051) |
1 | 0.35 | 300 | 4 | 1 | 0.053 | -0.015 (-0.049, 0.048) | Â |
1 | 0.35 | 300 | 3 | 2 | 0.103 | -0.021 (-0.087, 0.077) | Â |
0.5 | 0.05 | 25 | 4 | 1 | 0.176 | -0.043 (-0.159, 0.153) | -0.236 (-0.437, -0.060) |
0.5 | 0.05 | 25 | 3 | 2 | 0.343 | -0.064 (-0.280, 0.277) | -0.593 (-0.943, -0.300) |
0.5 | 0.05 | 300 | 4 | 1 | 0.049 | -0.013 (-0.047, 0.045) | Â |
0.5 | 0.05 | 300 | 3 | 2 | 0.096 | -0.019 (-0.082, 0.071) | Â |
0.5 | 0.35 | 25 | 4 | 1 | 0.155 | -0.066 (-0.199, 0.200) | -0.358 (-0.650, -0.150) |
0.5 | 0.35 | 25 | 3 | 2 | 0.314 | -0.091 (-0.311, 0.307) | -0.546 (-0.946, -0.245) |
0.5 | 0.35 | 300 | 4 | 1 | 0.044 | -0.020 (-0.060, 0.048) | Â |
0.5 | 0.35 | 300 | 3 | 2 | 0.085 | -0.031 (-0.104, 0.075) | Â |
1 | 0.05 | 25 | 9 | 1 | 0.101 | -0.030 (-0.080, 0.039) | -0.056 (-0.125, 0.013) |
1 | 0.05 | 25 | 5 | 5 | 0.479 | -0.063 (-0.270, 0.198) | Â |
1 | 0.05 | 300 | 9 | 1 | 0.031 | -0.006 (-0.022, 0.019) | Â |
1 | 0.05 | 300 | 5 | 5 | 0.138 | -0.014 (-0.075, 0.063) | Â |
1 | 0.35 | 25 | 9 | 1 | 0.101 | -0.033 (-0.086, 0.059) | -0.077 (-0.182, 0.011) |
1 | 0.35 | 25 | 5 | 5 | 0.481 | -0.068 (-0.274, 0.221) | Â |
1 | 0.35 | 300 | 9 | 1 | 0.032 | -0.007 (-0.025, 0.025) | Â |
1 | 0.35 | 300 | 5 | 5 | 0.144 | -0.015 (-0.080, 0.076) | Â |
0.5 | 0.05 | 25 | 9 | 1 | 0.105 | -0.019 (-0.072, 0.065) | -0.126 (-0.206, -0.045) |
0.5 | 0.05 | 25 | 5 | 5 | 0.477 | -0.042 (-0.250, 0.239) | Â |
0.5 | 0.05 | 300 | 9 | 1 | 0.030 | -0.005 (-0.021, 0.019) | Â |
0.5 | 0.05 | 300 | 5 | 5 | 0.130 | -0.013 (-0.072, 0.063) | Â |
0.5 | 0.35 | 25 | 9 | 1 | 0.102 | -0.026 (-0.086, 0.083) | -0.027 (-0.096, 0.071) |
0.5 | 0.35 | 25 | 5 | 5 | 0.467 | -0.062 (-0.281, 0.261) | Â |
0.5 | 0.35 | 300 | 9 | 1 | 0.017 | -0.017 (-0.036, 0.020) | Â |
0.5 | 0.35 | 300 | 5 | 5 | 0.094 | -0.043 (-0.110, 0.046) | Â |