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Table 2 Rate of recurrent sHPT after TPTX or TPTX+AT

From: Comparison of total parathyroidectomy without autotransplantation and without thymectomy versus total parathyroidectomy with autotransplantation and with thymectomy for secondary hyperparathyroidism: TOPAR PILOT-Trial

Reference TPTX+ AT n TPTX n Routinely performed thymectomy Mean length of follow – up (months) Recurrent sHPT1 (%)
Rothmund et al. 1991 [29] 20   yes 43 0
Zaraca et al. 1999 [58] 18   no, only if palpation was suspicious or parathyroid gland was missing 28 10
Walgenbach et al. 1997 [46] 67   yes 18 4.5
Walgenbach et al. 1998 [59] 86   yes 24 3.5
Henry et al.1990 [40] 152   no 30 10.5
Welk and Alix 1987 [60] 21   n.m. 33 24
Hampl et al. 1991 [37] 13   yes 33.5 76.5
Chou et al. 2002 [61] 75   n.m. 54 13.3
Bessell et al. 1993 84 42   n.m. 40 9.5
Dotzenrath et al. 2003 [62] 99   yes 51 6
Korzets et al. 1987 [63] 19   n.m. 6–60 26.3
Kinnaert et al. 2000 [31] 59   no 38 12
Tominaga et al. 1997 [39] 519   yes 36 10
     60 20
Ockert et al. 2002 [32] 11   no 38 45
   11 no 22.5 0
Kaye et al. 1993 [64]   13 n.m. 46 0
Higgins et al. 1991 [44] 34   no 72 80
   9 no 10 0
Nicholson 1996 [36] 13   no 24 16
   24 no 24 0
Saunders et al. 2005 [52]   55 no 29 4
Stracke et al. 1999 [35]   20 n.m. 20 4
Hampl et al. 1999 [65]   11 no 26 0
Ljutic D et al. 1994 [66]   43 no 104 2.3
  1. n.m. = not mentioned
  2. 1 Recurrent sHPT is defined as an increase of PTH > 5 fold above normal value after more than 6 months after initial PTX and after initial (postoperative) normalization of PTH.