Comparison of total parathyroidectomy without autotransplantation and without thymectomy versus total parathyroidectomy with autotransplantation and with thymectomy for secondary hyperparathyroidism: TOPAR PILOT-Trial

Table 2 Rate of recurrent sHPT after TPTX or TPTX+AT

Reference	TPTX+ AT n	TPTX n	Routinely performed thymectomy	Mean length of follow – up (months)	Recurrent sHPT¹ (%)
Rothmund et al. 1991 [29]	20		yes	43	0
Zaraca et al. 1999 [58]	18		no, only if palpation was suspicious or parathyroid gland was missing	28	10
Walgenbach et al. 1997 [46]	67		yes	18	4.5
Walgenbach et al. 1998 [59]	86		yes	24	3.5
Henry et al.1990 [40]	152		no	30	10.5
Welk and Alix 1987 [60]	21		n.m.	33	24
Hampl et al. 1991 [37]	13		yes	33.5	76.5
Chou et al. 2002 [61]	75		n.m.	54	13.3
Bessell et al. 1993 84	42		n.m.	40	9.5
Dotzenrath et al. 2003 [62]	99		yes	51	6
Korzets et al. 1987 [63]	19		n.m.	6–60	26.3
Kinnaert et al. 2000 [31]	59		no	38	12
Tominaga et al. 1997 [39]	519		yes	36	10
				60	20
Ockert et al. 2002 [32]	11		no	38	45
		11	no	22.5	0
Kaye et al. 1993 [64]		13	n.m.	46	0
Higgins et al. 1991 [44]	34		no	72	80
		9	no	10	0
Nicholson 1996 [36]	13		no	24	16
		24	no	24	0
Saunders et al. 2005 [52]		55	no	29	4
Stracke et al. 1999 [35]		20	n.m.	20	4
Hampl et al. 1999 [65]		11	no	26	0
Ljutic D et al. 1994 [66]		43	no	104	2.3

n.m. = not mentioned
¹ Recurrent sHPT is defined as an increase of PTH > 5 fold above normal value after more than 6 months after initial PTX and after initial (postoperative) normalization of PTH.

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