Table 1 Major inclusion criteria for each of the four cardiopathies.
From: M ulticenter randomi zed trial of cell the rapy in car diopat hies – MiHeart Study
Inclusion Criteria | Dilated Cardiomyopathy | Chagas Disease | Chronic Ischemic Heart Disease | Myocardial Infarction |
|---|---|---|---|---|
Age (years) | 18 to 65 | 18 to 75 | 30 to 75 | 30 to 80 |
Diagnosis of target disease | WHO criteria | 2 serologic test | typical angina with positive cardiac scintigraphy or MRI | WHO criteria |
Congestive heart failure | III – IV NYHA | III – IV NYHA | no | no |
Ischemia | no | no | II to IV CCS | not mandatory |
Left ventricular ejection fraction | ≤35% | ≤35% | 25%–55% | <50% |
Method | Simpson | Simpson | Simpson | Dodge |
Medical Therapy | Optimized | Optimized | Optimized | Optimized |