From: Outcome measurement in clinical trials for ulcerative colitis: towards standardisation
Score [ref] | 0 | 1 | 2 | 3 | 4 |
---|---|---|---|---|---|
Baron [ 21] | Normal: matt mucosa, ramifying vascular patter clearly visible, no spontaneous bleeding, no bleeding to light touch | Abnormal, but non-haemorrhagic: appearances between 0 and 2 | Moderately haemorrhagic: bleeding to light touch, but no spontaneous bleeding seen ahead of the instrument on initial inspection | Severely haemorrhagic: spontaneous bleeding seen ahead of instrument at initial inspection and bleeds to light touch | - |
Powell-Tuck [4] | Non-haemorrhagic (no bleeding spontaneously or on light touch) | Haemorrhagic (bleeding on light touch, but no spontaneous bleeding ahead of instrument) | Haemorrhagic (spontaneous bleeding seen ahead of instrument on initial inspection and bleeding to light touch) | - | - |
Rachmilewitz [7] | No granulation scattering light, normal vascular pattern, no mucosal vulnerability, no mucosal damage (mucus, fibrin, exudates, ulcer) | Faded or disturbed vascular pattern | Granulation scattering light, completely absent vascular pattern, contact bleeding, slight mucosal damage | Spontaneous bleeding,, pronounced mucosal damage | - |
Lémann [16] | Normal mucosa | Oedema and/or loss of mucosal vascularity, granularity | Friability (visible, induced bleeding on examination), petechiae | Spontaneous haemorrhage, visible ulcers | - |
Schroeder [5] | Normal or inactive disease | Mild (erythema, decreased vascular pattern, mild friability) | Moderate (marked erythema, absent vascular pattern, friability, erosions) | Severe (spontaneous bleeding, ulceration) | - |
Sutherland [6] | Normal | Mild friability | Moderate friability | Exudation, spontaneous haemorrhage | - |
Feagan [14] | Normal, smooth, glistening mucosa, with vascular pattern visible; not friable | Granular mucosa; vascular pattern not visible; not friable; hyperaemia | As 1, with a friable mucosa, but not spontaneously bleeding | As 2, but mucosa spontaneously bleeding | As 3, but clear ulceration; denuded mucosa |