Skip to main content

Table 2 Study flowchart.

From: A randomized, double blind, cross-over, placebo-controlled clinical trial to assess the effects of Candesartan on the insulin sensitivity on non diabetic, non hypertense subjects with dysglyce mia and abdominal obesity. "ARAMIA"

Visit

Screening

A

B

1

2

3

4

5

6

7

1a

2a

3a

4a

5a

6a

7a

8a

 

Week

-4

-3

-1

0

1

4

8

12

16

20

24

25

28

32

36

40

44

48

52

Passive Follow up

                  

x

Nurse interview

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

 

MD interview

 

x

x

x

x

x

 

x

  

x

x

x

 

x

  

x

 

Medication delivery

 

x

 

x

 

x

x

x

x

x

x

 

x

x

x

x

x

  

Physical examination

x

  

x

x

x

 

x

  

x

x

x

 

x

  

x

 

Randomization

   

x

               

Sample withdrawing

 

x

x

  

x

 

x

  

x

 

x

    

x

 

Sample storage

  

x

       

x

      

x

 

ECG

  

x

                

Hemogram

  

x

       

x

      

x

 

Plasma glycemia

     

x

 

x

    

x

 

x

    

Lipid Profile

 

x

        

x

      

x

 

Hepatic Function test

 

x

        

x

      

x

 

Renal Function test

 

x

        

x

      

x

 

OGTT

 

x

        

x

      

x

 

Insulin

  

x

       

x

      

x

 

CRP

   

x

      

x

      

x

 

IL-6

   

x

      

x

      

x

 

Hb A1c

   

x

      

x

      

x

 

Leptin

   

x

      

x

      

x

 

Resistin

   

x

      

x

      

x

 

Adiponectin

   

x

      

x

      

x

 

TPA

   

x

      

x

      

x

 

PAI-1

   

x

      

x

      

x

 

8-Isoprostanes

   

x

      

x

      

x

 

Malonaldehyde

   

x

      

x

      

x

 

Oxi/Red Glutathione

   

x

      

x

      

x

Â