Visit | Screening | A | B | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 1a | 2a | 3a | 4a | 5a | 6a | 7a | 8a | Â |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Week | -4 | -3 | -1 | 0 | 1 | 4 | 8 | 12 | 16 | 20 | 24 | 25 | 28 | 32 | 36 | 40 | 44 | 48 | 52 |
Passive Follow up | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | x |
Nurse interview | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | Â |
MD interview | Â | x | x | x | x | x | Â | x | Â | Â | x | x | x | Â | x | Â | Â | x | Â |
Medication delivery | Â | x | Â | x | Â | x | x | x | x | x | x | Â | x | x | x | x | x | Â | Â |
Physical examination | x | Â | Â | x | x | x | Â | x | Â | Â | x | x | x | Â | x | Â | Â | x | Â |
Randomization | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Sample withdrawing | Â | x | x | Â | Â | x | Â | x | Â | Â | x | Â | x | Â | Â | Â | Â | x | Â |
Sample storage | Â | Â | x | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
ECG | Â | Â | x | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Hemogram | Â | Â | x | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
Plasma glycemia | Â | Â | Â | Â | Â | x | Â | x | Â | Â | Â | Â | x | Â | x | Â | Â | Â | Â |
Lipid Profile | Â | x | Â | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
Hepatic Function test | Â | x | Â | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
Renal Function test | Â | x | Â | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
OGTT | Â | x | Â | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
Insulin | Â | Â | x | Â | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
CRP | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
IL-6 | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
Hb A1c | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
Leptin | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
Resistin | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
Adiponectin | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
TPA | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
PAI-1 | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
8-Isoprostanes | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
Malonaldehyde | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |
Oxi/Red Glutathione | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â | Â | Â | Â | Â | Â | x | Â |