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Table 3 Differences (mean ± SD) in BMD at the total hip and heel in nitrate users and nonusers. Unadjusted and after adjusting for estrogen use and baseline differences (26).

From: The effects of organic nitrates on osteoporosis: a randomized controlled trial [ISRCTN94484747]

 

Percent difference in BMD (95% CI)

 

Daily – nonusers

Intermittent – nonusers

Hip BMD

  

Unadjusted

0 (-2.7 to 1.4)

0 (-4.1 to 4.1)

Adjusted*

1.3 (0.14 to 4.1)

2.6 (0.4 to 6.8)

Heel BMD

  

Unadjusted

-2.6 (-5.3 to 0)

0 (-5.3 to 7.9)

Adjusted*

0 (-2.6 to 2.6)

5.3 (2.6 to 11)

  1. *Adjusted for estrogen use and baseline differences (37), which are current alcohol intake, walks for exercise, physical activity, self-reported health status, falls in the past 12 months, thiazide and nonthiazide diuretic use, inability to rise from a chair independently and frail on physical examination.