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Table 1 Effect of conjugated estrogen and transdermal nitroglycerin on BMD in ovariectomized rats 25.

From: The effects of organic nitrates on osteoporosis: a randomized controlled trial [ISRCTN94484747]

Treatment group, n = 5 for all groups Percent increase in BMD (L2-L4) over 6 weeks
Sham operated 25% ± 2%
Ovariectomized rats 8% ± 3%
Ovariectomized + estrogen 27% ± 5%*
Ovariectomized + transdermal nitroglycerin 20% ± 3%†
Ovariectomized + estrogen + nitroglycerin 22% ± 2%*
  1. *Different than ovariectomized rats at p < 0.005
  2. † Different than ovariectomized rats at p < 0.02