Study flow diagram. The study will recruit 320 participants with chronic low back pain from Boston Medical Center and surrounding affiliated federally qualified community health centers. Participants are randomized after baseline data collection to yoga classes, physical therapy (PT), or education through a self-care book in a 2:2:1 ratio. This year-long study is divided into a 12-week Treatment Phase and subsequent 40-week Maintenance Phase. Yoga and PT participants who have attended at least one intervention session during the Treatment Phase are re-randomized at 12 weeks into a structured maintenance intervention or no structured maintenance intervention. For the participants, we term the no structured maintenance intervention as “Home Practice” only. Education participants continue through the study without any re-randomization.