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Table 7 Consent processes and understanding of the trial (Household survey)

From: Complex realities: community engagement for a paediatric randomized controlled malaria vaccine trial in Kilifi, Kenya

  Site A Site B Site C Total
  n = 67 (%) n = 33 (%) n = 100 (%) n = 200 (%)
Main purpose of the trial     
Provide treatment/help to participating children 32 (47.8) 18 (54.5) 71 (71.0) 121 (60.5)
Learn about potential for preventing malaria 27 (40.3) 12 (36.4) 23 (23.0) 62 (31.0)
DK 3 (4.5) 1 (3.0) 3 (3.0) 7 (3.5)
Other activities 2 (3.0) 0 2 (2.0) 4 (2.0)
Missing/data not clear to code 3(4.5) 2 (6.1) 1 (1.0) 6 (3.0)
Did all children in the trial get a malaria vaccine?     
Yes 38 (56.7) 19 (57.6) 63 (63.0) 120 (60.0)
No 12 (17.9) 6 (18.2) 11 (11.0) 29 (14.5)
DK 17 (25.4) 8 (24.2) 24 (24.0) 49 (24.5)
Missing data 0 0 2 (2.0) 2 (1.0)
Do you think children who got trial vaccines are still able to get malaria?     
Yes 10 (14.9) 5 (15.2) 15 (15.0) 30 (15.0)
No 32 (47.8) 17 (51.5) 56 (56.0) 105 (52.5)
DK 25 (37.3) 11 (33.3) 28 (28.0) 64 (32.0)
Missing data 0 (0) 0 1 (1.0) 1 (0.5)
Would consider participating in future similar trial?     
Agree 45 (67.2) 20 (60.6) 80 (80.0) 145 (72.5)
Not agree 2 (3.0) 0 0 2 (1.0)
Indifferent/DKa 20 (29.9) 13 (39.4) 20 (20.0) 53 (26.5)
Content with decision to enrol your child in the trial?     
Yes 61 (91.0) 31 (93.9) 94 (94.0) 186 (93.0)
No 4 (6.0) 0 2 (2.0) 6 (3.0)
Indifferent 2 (3.0) 2 (6.1) 4 (4.0) 8 (4.0)
Most important reasons for enrolling in trial (top five)     
Access to free treatment 18 (26.9) 10 (30.3) 35 (35.0) 63 (31.5)
Access to better and quality services 9 (13.4) 6 (18.2) 25 (25.0) 40 (20.0)
Vaccine beneficial 12 (17.9) 5 (15.2) 13 (13.0) 30 (15.0)
Detailed explanation of the study 5 (7.5) 3 (9.1) 7 (7.0) 15 (7.5)
Previous experience/interaction with KEMRI 3 (4.5) 4 (12.1) 6 (6.0) 13 (6.5)
  1. aHere most people reported they would first want to hear more about what the trial would involve at the point of information giving before making their decision.
  2. DK; do not know.