Table 5 Number and percentage of trials classed as ‘successfully recruiting’ based on stopping boundaries of 30% or 40%
From: An investigation of the impact of futility analysis in publicly funded trials
Number (percentage) of trials successfully recruiting | ‘Successful’ recruitment | |||||
|---|---|---|---|---|---|---|
CP stopping boundary 20% | CP stopping boundary 30% | CP stopping boundary 40% | ||||
Yes | No | Yes | No | Yes | No | |
50% of patients | 15 (45%) | 18 (55%) | 15 (45%) | 18 (55%) | 15 (45%) | 18 (55%) |
60% of patients | 15 (45%) | 18 (55%) | 17 (52%) | 16 (48%) | 21 (64%) | 12 (36%) |
70% of patients | 19 (58%) | 14 (42%) | 20 (61%) | 13 (39%) | 21 (64%) | 12 (36%) |
75% of patients | 19 (58%) | 14 (42%) | 21 (64%) | 12 (36%) | 21 (64%) | 12 (36%) |
80% of patients | 19 (58%) | 14 (42%) | 20 (61%) | 13 (39%) | 20 (61%) | 13 (39%) |
90% of patients | 19 (58%) | 14 (42%) | 19 (58%) | 14 (42%) | 19 (58%) | 14 (42%) |