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Table 4 Dexamethasone-reducing regimen

From: CryptoDex: A randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial

Period

Dexamethasone Dose

Timing

Week 1

0.3 mg/kg iv

Once daily

Week 2

0.2 mg/kg iv

Once daily

Week 3

0.1 mg/kg po

Once daily

Week 4

3.0 mg total/day po

Once daily

Week 5

2.0 mg total/day po

Once daily

Week 6

1.0 mg total/day po

Once daily

Week 7 onwards

Stops