Clinical stage 1 | Asymptomatic |
Persistent generalised lymphadenopathy (PGL) | |
Performance scale 1: asymptomatic, normal activity | |
Clinical stage 2 | Weight loss, <10% of body weight |
Minor mucocutaneous manifestations (seborrheic dermatitis, prurigo, fungal nail infections, recurrent oral ulcerations, angular cheilitis) | |
Herpes zoster, within the last 5Â years | |
Recurrent upper respiratory tract infections (for example, bacterial sinusitis) | |
And/or performance Scale 2: symptomatic, normal activity. | |
Clinical stage 3 | Weight loss, >10% of body weight |
Unexplained chronic diarrhoea, >1Â month | |
Unexplained prolonged fever (intermittent or constant), >1Â month | |
Oral candidiasis (thrush) | |
Oral hairy leukoplakia | |
Pulmonary tuberculosis, within the past year. | |
Severe bacterial infections (for example, pneumonia, pyomyositis) | |
And/or Performance scale 3: bedridden, <50% of the day during the last month | |
Clinical stage 4 | HIV wasting syndrome, as defined by CDC1 |
Pneumocystis carinii pneumonia | |
Toxoplasmosis of the brain | |
Cryptosporidiosis with diarrhoea, >1Â month | |
Cryptococcosis, extrapulmonary | |
Cytomegalovirus (CMV) disease of an organ other than liver, spleen, or lymph nodes | |
Herpes simplex virus (HSV) infection, mucocutaneous >1Â month, or visceral of any duration | |
Progressive multifocal leukoencephalopathy (PML) | |
Any disseminated endemic mycosis (for example, histoplasmosis, coccidioidomycosis) | |
Candidiasis of the oesophagus, trachea, bronchi, or lungs | |
Atypical mycobacteriosis, disseminated | |
Nontyphoid Salmonella septicaemia | |
Extrapulmonary tuberculosis | |
Lymphoma | |
Kaposi sarcoma (KS) | |
HIV encephalopathy, as defined by CDC2 | |
And/or Performance scale 4: bedridden, >50% of the day during the last month |