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Figure 4 | Trials

Figure 4

From: Long-term outcome of the humoral and cellular immune response of an H5N1 adjuvanted influenza vaccine in elderly persons: 2-year follow-up of a randomised open-label study

Figure 4

Neutralising antibody response against A/Vietnam/1194/2004 in the AS03 A -adjuvanted groups. Vaccination groups are: 1xH5N1-AS, single dose of the AS03A-adjuvanted vaccine; 1xH5N1, single dose of the non-adjuvanted vaccine; 2xH5N1-AS, double dose of the AS03A-adjuvanted vaccine; 2xH5N1, double dose of the non-adjuvanted vaccine. Seroconversion rate (SCR) was defined as the percentage of vaccinees with a ≥4-fold increase in neutralising antibody titre at post-vaccination. GMT, geometric mean titre. Error bars indicate the 95% confidence intervals. Post-vaccination = day 42 (data also shown in [13]). Post-vaccination results are shown for a subset of the according-to-protocol immunogenicity cohort (1xH5N1-AS: N =87, 2xH5N1-AS: N =82), month 12 and month 24 results for a subset of the month 24 according-to-protocol persistence cohort (1xH5N1-AS: N =51, 2xH5N1-AS: N =54); N = maximum number of participants with available results.

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