Table 1 Patient characteristics and medical history at baseline (intent-to-treat population)
HA/CMC powder (n = 105) | No adhesion barrier (n = 104) | P value | |
|---|---|---|---|
Age in years, mean ± SD | 57.6 ± 16.3 | 56.1 ± 16.5 | 0.531 |
Men, n (%) | 53 (50.5) | 51 (49.0) | 0.835 |
BMI in kg/m2, mean ± SD | 24.7 ± 4.0 | 24.3 ± 4.2 | 0.451 |
Smoking history, n (%) | 0.676 | ||
Current smoker | 16 (15.8) | 18 (17.8) | |
Ex-smoker | 19 (18.8) | 23 (22.8) | |
Non-smoker | 66 (65.3) | 60 (59.4) | |
Previous abdominal/pelvic surgery, n (%) | 58 (55.2) | 61 (58.7) | 0.618 |
Diabetes, n (%) | 10 (9.6) | 5 (4.8) | 0.180 |
Pre-operative diagnosis, n (%) | 0.566 | ||
Cancer | 48 (45.7) | 44 (42.3) | |
Diverticulosis | 27 (25.7) | 36 (34.6) | |
Crohn’s disease | 11 (10.5) | 7 (6.7) | |
Ulcerative colitis | 5 (4.8) | 7 (6.7) | |
Polyp (no cancer) | 5 (4.8) | 5 (4.8) | |
Other | 5 (4.8) | 1 (1.0) | |
Endometriosis | 2 (1.9) | 3 (2.9) | |
Polyposis | 2 (1.9) | 1 (1.0) | |
ASA Physical Status classification, n (%) | 0.537 | ||
P1 | 37 (35.2) | 41 (39.4) | |
P2 | 60 (57.1) | 52 (50.0) | |
P3 | 8 (7.6) | 11 (10.6) | |
Concomitant diseases (≥20% patients in either group), n (%) | |||
Gastrointestinal, hepatic | 46 (43.8) | 39 (37.5) | 0.353 |
Cardiovascular | 31 (29.5) | 35 (33.7) | 0.521 |
Metabolic, endocrine, nutritional | 38 (36.2) | 26 (25.0) | 0.079 |
Allergic | 18 (17.1) | 31 (29.8) | 0.031 |
Concomitant medications (≥10% patients in either group), n (%) | |||
Heparin | 51 (48.6) | 47 (45.2) | ND |
Combination of penicillins* | 17 (16.2) | 9 (8.7) | ND |