Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM): study protocol for a randomized controlled trial

Table 1 nine-month study regimen drugs and doses

Product	Weight group
Product	Less than 33 kg	33 to 50 kg	More than 50 kg
Moxifloxacin	400 mg	600 mg	800 mg
Clofazimine	50 mg	100 mg	100 mg
Ethambutol	800 mg	800 mg	1200 mg
Pyrazinamide	1000 mg	1500 mg	2000 mg
Isoniazid*	300 mg	400 mg	600 mg
Prothionamide*	250 mg	500 mg	750 mg
Kanamycin*	15 mg per kilogram body weight (maximum 1 g)

*Given only during the 16-week intensive phase which can be extended to 20 or 24 weeks in the event of delayed smear conversion.

ISSN: 1745-6215