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Table 1 Endpoints

From: Understanding of chest pain in microvascular disease proved by cardiac magnetic resonance image (UMPIRE): study protocol for a randomized controlled trial

 

Endpoint details

Primary endpoint

>25% improvement in perfusion defect size in adenosine-stress CMR from baseline to three months after udenafil treatment

Secondary endpoints

<25% improvement in perfusion defect size in adenosine-stress CMR from baseline to three months after udenafil treatment

Decrement of frequency of chest pain

Improvement of ST-depression in stress test

Improvement of Duke score in stress test

Improvement of QoL assessment by SF-36 questionnaire

Improvement of sexual dysfunction assessment by BISF-W self-questionnaire

Improvement of biomarkers for endothelial function

  1. CMR; Cardiac magnetic resonance image, QoL; Quality of life.
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Trials

ISSN: 1745-6215