Table 1 Surviving Sepsis Campaign Guideline definitions of sepsis

Sepsis

SIRS plus new-suspected infection

Severe sepsis

Sepsis plus sepsis-induced organ dysfunction

Organ dysfunction

Sepsis-induced hypotension

Lactate > normal laboratory results

Urine output <0.5 mL/kg/hour for >2 hours despite adequate fluid resuscitation

ALI with PaO₂/FiO₂ < 250 in the absence of pneumonia as infection source

ALI with PaO₂/FiO₂ < 200 in the presence of pneumonia as infection source

Creatinine >176.8 mmol/L

Bilirubin >34.2 mmol/L

Platelet count >100,000/mm³

Coagulopathy (INR >1.5)

Septic shock

Severe sepsis plus hypotension not reversed by fluid resuscitation