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Table 4 Baseline characteristics and echocardiographic data of patients with or without a significant improvement in LVEF (>10%) at follow-up

From: Left ventricular remodeling after acute myocardial infarction: the influence of viability and revascularization - an echocardiographic substudy of the VIAMI-trial

Characteristic No improvement (n = 148) Improvement (n = 76) P value*
Male 80% 70% 0.09
Age (years) 61 61 0.75
Clinical history
Angina 44% 49% 0.50
Myocardial infarction 7% 7% 0.96
Percutaneous coronary intervention 5% 5% 0.86
Coronary artery bypass graft 0% 0% -
In-hospital and follow-up
Anterior infarction 38% 39% 0.81
Thrombolysis 51% 51% 0.93
Peak creatine kinase (U/L) 1802 ± 1439 1567 ± 1245 0.22
Peak creatine kinase-MB (U/L) 185 ± 150 166 ± 159 0.39
Pathological Q waves (n) 2.1 ± 1.76 1.9 ± 1.58 0.53
Persistent ST elevation > 1 mm 34% 32% 0.67
Revascularization before follow-up 43% 62% 0.008
Echocardiography
Viable segments (16 segments model) (n) 2.3 ± 1.71 3.2 ± 1.78 <0.001
LVEDV (ml) 89.34 ± 32.44 99.84 ± 27.78 0.012
LVESV (ml) 38.91 ± 21.12 54.84 ± 22.03 <0.001
LV EF (%) 57.66 ± 10.93 45.87 ± 10.31 <0.001
WMI 1.51 ± 0.25 1.62 ± 0.31 0.01
follow-up echocardiogram (days) 208 ± 133 201 ± 127 0.70
Risk factors
Diabetes mellitus 9% 12% 0.50
Hypertension 29% 24% 0.35
Hypercholesterolemia 16% 17% 0.83
Current cigarette smoking 46% 47% 0.91
Family history of coronary artery disease 26% 29% 0.61
Medications at admission
Aspirin 12% 13% 0.74
Beta-blocker 13% 13% 0.96
Statins 10% 12% 0.60
ACE-inhibitor 11% 7% 0.27
Angiotensin II antagonist 7% 3% 0.09
Medications at discharge
Aspirin 94% 95% 0.80
Beta-blocker 95% 93% 0.73
Statins 95% 95% 0.96
ACE-inhibitor 57% 63% 0.36
Angiotensin II antagonist 6% 5% 0.80
Clopidogrel 32% 45% 0.08
Diuretics 8% 9% 0.79
  1. *Differences between the groups. On the electrocardiogram at 48 hours after acute myocardial infarction. Values are shown as means ± SD unless otherwise indicated. ACE, angiotensin converting enzyme; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume; WMI, wall motion score index.