Characteristic | No improvement (n = 148) | Improvement (n = 76) | P value* |
---|---|---|---|
Male | 80% | 70% | 0.09 |
Age (years) | 61 | 61 | 0.75 |
Clinical history | |||
Angina | 44% | 49% | 0.50 |
Myocardial infarction | 7% | 7% | 0.96 |
Percutaneous coronary intervention | 5% | 5% | 0.86 |
Coronary artery bypass graft | 0% | 0% | - |
In-hospital and follow-up | |||
Anterior infarction | 38% | 39% | 0.81 |
Thrombolysis | 51% | 51% | 0.93 |
Peak creatine kinase (U/L) | 1802 ± 1439 | 1567 ± 1245 | 0.22 |
Peak creatine kinase-MB (U/L) | 185 ± 150 | 166 ± 159 | 0.39 |
Pathological Q waves (n)†| 2.1 ± 1.76 | 1.9 ± 1.58 | 0.53 |
Persistent ST elevation > 1 mm†| 34% | 32% | 0.67 |
Revascularization before follow-up | 43% | 62% | 0.008 |
Echocardiography | |||
Viable segments (16 segments model) (n) | 2.3 ± 1.71 | 3.2 ± 1.78 | <0.001 |
LVEDV (ml) | 89.34 ± 32.44 | 99.84 ± 27.78 | 0.012 |
LVESV (ml) | 38.91 ± 21.12 | 54.84 ± 22.03 | <0.001 |
LV EF (%) | 57.66 ± 10.93 | 45.87 ± 10.31 | <0.001 |
WMI | 1.51 ± 0.25 | 1.62 ± 0.31 | 0.01 |
follow-up echocardiogram (days) | 208 ± 133 | 201 ± 127 | 0.70 |
Risk factors | |||
Diabetes mellitus | 9% | 12% | 0.50 |
Hypertension | 29% | 24% | 0.35 |
Hypercholesterolemia | 16% | 17% | 0.83 |
Current cigarette smoking | 46% | 47% | 0.91 |
Family history of coronary artery disease | 26% | 29% | 0.61 |
Medications at admission | |||
Aspirin | 12% | 13% | 0.74 |
Beta-blocker | 13% | 13% | 0.96 |
Statins | 10% | 12% | 0.60 |
ACE-inhibitor | 11% | 7% | 0.27 |
Angiotensin II antagonist | 7% | 3% | 0.09 |
Medications at discharge | |||
Aspirin | 94% | 95% | 0.80 |
Beta-blocker | 95% | 93% | 0.73 |
Statins | 95% | 95% | 0.96 |
ACE-inhibitor | 57% | 63% | 0.36 |
Angiotensin II antagonist | 6% | 5% | 0.80 |
Clopidogrel | 32% | 45% | 0.08 |
Diuretics | 8% | 9% | 0.79 |