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Table 1 Overall hazard ratio and test statistics for the GOG111 and PATCH trials

From: An approach to trial design and analysis in the era of non-proportional hazards of the treatment effect

Trial

Hazard ratio

Joint test

Cox test of HR = 1

G-T test of PH

 

Est.

95% CI

Chi-sq.

P

Chi-sq.

P

Chi-sq.

P

GOG111

0.73

(0.59,0.90)

15.90

0.0004

8.38

0.0038

7.52

0.0061

PATCH1

0.71

(0.50,1.00)

7.58

0.023

3.78

0.052

3.80

0.051

  1. Est. = estimate, Chi-sq. = chi-square.