From: Sample size calculations in pediatric clinical trials conducted in an ICU: a systematic review
Characteristic | N(%) |
---|---|
Type of primary outcome | Â |
 Dichotomous | 30 (42) |
 Continuous | 39 (55) |
 Unclear | 2 (3) |
A priori sample size calculation | Â |
 At least power reported | 49 (69) |
  → Of these |  |
    NP reported | 35 (71) |
 NP reported as proportion of total | 35 (49) |
 No report of a priori sample size calculation | 22 (31) |
Information source of NP assumption | Â |
  → Of the 49 trials that report at least power |  |
    Literature | 21 (43) |
    Own experience | 9 (18) |
    Pilot study | 6 (12) |
    Not reported | 13 (27) |
  → Of the 35 trials that report an assumed NP value |  |
    Literature | 14 (40) |
    Own experience | 8 (23) |
    Pilot study | 6 (17) |
    Not reported | 7 (20) |