Table 2 Histopathological changes, grading and scoring ^a

Chronic inflammation

Normal or number of mononuclear cells less than 5/high power field

0

+ (mild): Some chronic inflammatory cells are localized in the superficial layer of the mucosa, but not more than 1/3 of the depth of the mucosa;

1

++ (moderate): A more dense accumulation of chronic inflammatory cells, but not exceeding 2/3 of the depth of the mucosa

2

+++ (severe): A dense accumulation of chronic inflammatory cells occupying the whole depth of the mucosa

3

Active chronic inflammation

Normal

0

+ (mile): Few neutrophils in the lamina propria of the mucosa

1

++ (moderate): More neutrophils in the mucosal layer and between superficial epithelial cells, pit epithelial cells and glandular epithelial cells.

2

+++ (severe): A more dense infiltration of neutrophils, or abscess on pits can be seen in addition to what is seen in moderate activity.

3