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Table 6 Results on symptom severity, quality of life, and body constitution in the three groups at four measurements and comparisons using GEE (n = 240)

From: The effects of two Chinese herbal medicinal formulae vs. placebo controls for treatment of allergic rhinitis: a randomised controlled trial

 

CS (n = 81)

YS (n = 80)

Placebo (n = 79)

GEE (Group × Time)

 

T1

T2

T3

T4

T1

T2

T3

T4

T1

T2

T3

T4

 

Mean

Mean

Mean

Mean

Mean

Mean

Mean

Mean

Mean

Mean

Mean

Mean

  

(SE)

(SE)

(SE)

(SE)

(SE)

(SE)

(SE)

(SE)

(SE)

(SE)

(SE)

(SE)

Wald χ 2

P

SS total score

102.93 (5.33)

61.21 (5.33)

51.42 (5.33)

42.29 (5.33)

101.59 (5.37)

66.49 (5.37)

62.21 (5.37)

49.76 (5.37)

105.93 (5.40)

87.34 (5.40)

84.06 (5.40)

76.83 (5.40)

24.49

<0.0005

QOL total score

59.73 (2.78)

37.54 (2.78)

32.56 (2.78)

29.22 (2.78)

58.91 (2.80)

41.78 (2.80)

37.86 (2.80)

33.34 (2.80)

60.87 (2.82)

50.35 (2.82)

49.32 (2.82)

45.08 (2.82)

19.47

0.003

Body constitution

              

Gentleness

55.31 (1.40)

60.90 (1.40)

61.99 (1.40)

61.91 (1.40)

53.47 (1.40)

57.73 (1.42)

59.15 (1.41)

60.64 (1.41)

52.42 (1.41)

54.72 (1.42)

56.06 (1.42)

59.97 (1.42)

9.02

0.17

Qi-deficiency

42.85 (1.80)

35.05 (1.80)

33.58 (1.80)

33.57 (1.80)

39.56 (1.80)

37.50 (1.82)

36.43 (1.82)

34.82 (1.82)

44.83 (1.81)

42.92 (1.83)

40.05 (1.83)

39.27 (1.82)

15.98

0.01

Yang-deficiency

38.25 (2.13)

29.46 (2.17)

28.57 (2.17)

28.26 (2.15)

39.36 (2.16)

34.54 (2.19)

33.96 (2.19)

33.29 (2.16)

42.32 (2.16)

37.99 (2.18)

34.99 (2.19)

35.17 (2.17)

6.75

0.35

Inherited special

41.07 (1.71)

32.43 (1.72)

31.33 (1.71)

29.36 (1.71)

39.77 (1.72)

34.37 (1.74)

32.13 (1.73)

32.09 (1.73)

39.86 (1.73)

37.65 (1.74)

33.91 (1.74)

36.49 (1.74)

16.58

0.01

  1. SS, Symptom severity; QOL, Quality of life; CS, Cure-allergic-rhinitis Syrup group; YS, Yu-ping-feng San group; GEE, Generalised Estimating Equation test.
  2. T1, baseline at subject recruitment; T2, immediately after intervention; T3, one month after intervention; T4, three months after intervention.