Prognosis after ST-elevation myocardial infarction: a study on cardiac magnetic resonance imaging versus clinical routine

Table 3 Traditional outcome markers and CMR parameters: association with mortality in univariable and stepwise multivariable Cox regression analysis

	Univariable analysis		Stepwise multivariable analysis
Variable	HR (95% CI)	P value	HR (95% CI)	P value
Male gender	1.24 (0.42–3.60)	0.70	not included	-
Hyperlipidemia	0.81 (0.29–2.27)	0.69	not included	-
Serum creatinine, μmol/l	1.01 (0.98–1.03)	0.64	not included	-
CK-MB_max, μmol/l	1.04 (0.99–1.08)	0.08	-	-
TIMI-risk score	1.31 (1.07–1.60)	0.009	-	-
ST-segment resolution, %	0.99 (0.98–1.01)	0.07	not included	-
TIMI-flow pre-PCI 0	1.20 (0.83–1.75)	0.32	not included	-
TIMI-flow post-PCI 0-II	4.39 (1.73–11.15)	0.002	-	-
LV-EF_echo, %	0.94 (0.89–0.98)	0.005	-	-
Time-to-revascularization, min	1.00 (0.99–1.01)	0.25	not included	-
LV-EF_CMR, %	0.95 (0.92–0.98)	0.003	-	-
Infarct size, %LV	1.07 (1.04–1.10)	<0.001	-	-
MO, %LV	1.09 (1.02–1.21)	0.01	-	-
MSI	0.93 (0.92–0.95)	<0.001	0.93 (0.90–0.95)	<0.001

%LV = percentage of left ventricular mass; CI = confidence interval; CK-MB_max = maximum level of creatine kinase-MB; CMR = cardiac magnetic resonance imaging; HR = hazard ratio; LV-EF_CMR = left ventricular ejection fraction assessed by CMR; LV-EF_echo = left ventricular ejection fraction assessed by echocardiography; MO = microvascular obstruction; MSI = myocardial salvage index; PCI = percutaneous coronary intervention; TIMI = Thrombolysis In Myocardial Infarction.

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