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Table 2 Implementation evaluation domains, outcomes measures, and data sources

From: INtegration of DEPression Treatment into HIV Care in Uganda (INDEPTH-Uganda): study protocol for a randomized controlled trial

RE-AIM Domain

Outcome measure

Sample

Data source

Reach

% screened with PHQ-2

All adult clinic patients

Routine data abstraction (Triage Book)

% screened positive (PHQ-2 > 2)

All adult clinic patients

Routine data abstraction (Triage Book)

Accuracy of positive screens assessed with PHQ survey data from patient longitudinal cohort

% positive screens who receive further evaluation (PHQ-9/MINI)

Patient cohort

Routine data abstraction (clinic charts)

% positive screens who are depressed (PHQ-9 > 9)

Patient cohort

Routine data abstraction (clinic charts)

Accuracy of provider PHQ-9 assessed with PHQ survey data

% depressed who receive antidepressants (treatment uptake)

Patient cohort subset (baseline PHQ-9 > 9)

Routine data abstraction (Depression Treatment Registry)

Adoption

Provider knowledge, attitudes and practices regarding depression care

Provider cohort

Provider survey data

Implementation quality (fidelity)

Initial prescription: Appropriate diagnosis, treatment prescription (medication and dose)

Clinic level data

Supervision log data (aggregate data from monthly chart reviews of newly prescribed patients)

Treatment management: Appropriate assessment of symptoms, side effects, and prescription (medication and dose)

Clinic level data

Supervision log data (aggregate data from monthly chart reviews of ongoing treatment patients)

Effectiveness

Alleviation of depression

Patient cohort subset (baseline PHQ-9 > 9)

Patient PHQ-9 survey data

Improvement in condom use, work status and ART adherence

Patient cohort subset (baseline PHQ-9 > 9)

Patient survey data

  1. Legend: PHQ, Patient Health Questionnaire.