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Table 6 Illustrating the effect on sample size and participant characteristics at baseline of varying participant selection criteria in the stroke trial. CPRD, Clinical Practice Research Datalink.

From: Cluster randomized trials utilizing primary care electronic health records: methodological issues in design, conduct, and analysis (eCRT Study)

 

Number

Age

Gender

Systolic blood pressure

Total cholesterol

  

Mean (SD)

Female (%)

Mean (SD)

Mean (SD)

Participants with prevalent stroke

     

All Non-trial CPRD practices

47,887

72.2 (14.0)

23,179 (48)

134.4 (15.3)

4.4 (1.0)

Trial practices

11,391

72.5 (14.0)

5,490 (48)

134.5 (15.6)

4.4 (1.0)

Participants with incident stroke since start of CPRD record

   

All Non-trial CPRD practices

27,971

72.5 (13.4)

13,369 (48)

134.8 (15.1)

4.4 (1.0)

Trial practices

6,296

72.5 (13.4)

2,950 (47)

135.0 (15.4)

4.4 (1.0)

Participants with incident stroke within two years of intervention start date

  

All Non-trial CPRD practices

7,530

71.4 (14.0)

3,629 (48)

136.6 (15.6)

4.5 (1.10)

Trial practices

1,706

72.0 (14.1)

797 (47)

136.3 (16.5)

4.5 (1.10)