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Table 3 Specification of measurements per blood sample

From: METFORMIN: an efficacy, safety and pharmacokinetic study on the short-term and long-term use in obese children and adolescents – study protocol of a randomized controlled study

Visit Measurements
  Fasted glucose Fasted insulin OGTT (Glucose and insulin at t = 0, 30, 60, 90 and 120’) HbA1c Blood count, indices Urea, creatinine ALAT Lipid profile Vitamin B12 CRP DNA Metformin DNA
Part 1
0    x x x x x x x x x x x
3             x  
5             x  
13 x x     x x      x  
25 x x   x x x x   x    x  
37    x    x x      x*  
49 x x   x x x x   x    x  
61 x x     x x       
73    x x x x x x x x   x  
Part 2
98 x x   x x x x   x     
122 x x   x x x x   x     
146    x x x x x x x x    
  1. ALAT, Alanine aminotransferase; CRP, C-reactive protein; HbA1c, Glycated haemoglobin; OGTT, Oral glucose tolerance test.
  2. *Metformin day-curve (baseline sample and five subsequent samples).