Skip to main content

Table 2 Measurements during parts 1 and 2 of the study

From: METFORMIN: an efficacy, safety and pharmacokinetic study on the short-term and long-term use in obese children and adolescents – study protocol of a randomized controlled study

Visit Measurements
  Adverse events Co-medication History Physical examination Blood sampling Urine sampling OGTT Metformin day-curve Bio-impedance PWV Fitness test IWQOL questionnaire Dietary diary Calorimetryc DEXA scanc
Part 1
0    x xd x x x   x x x x x x x
1a x x              
3 x x    x           
5 x x    x           
9a x x              
13 x x   x x           
17a x x              
21a x x              
25 x x   x x           
29a x x              
33a x x              
37 x x   xd x   x x x   x x x   x
41a x x              
45a x x              
49 x x   x x           
53a x x              
57a x x              
61 x x   x x           
65a x x              
69a x x              
73 x x   xd x x x   x x x x x x x
Part 2
86b x x              
98 x x   x x           
110b x x              
122 x x   x x           
134b x x              
146 x x   x x x x   x x x x x   x
  1. IWQOL, Impact of weight on quality of life; OGTT, Oral glucose tolerance test; PWV, Pulse wave velocity; aPhone calls; bVisit for metformin user, phone call for non-user; cPerformed in subsample in one of the study centres; dExtensive examination.