Table 3 Main inclusion and exclusion criteria – Part B

Inclusion criteria

1. All inclusion criteria detailed in Table 1 (Part A)

2. Human leukocyte antigen class I and/or class II DSA-positivity

3. Morphological and immunohistochemical AMR features (Table 2)

Exclusion criteria

1. All exclusion criteria detailed in Table 1 (Part A)

2. Laboratory tests

 Thrombocytopenia <30 g/l within 2 weeks before enrolment

 Neutrophil count <1 g/l within 2 weeks before enrolment

4. Peripheral neuropathy ≥ grade 2

5. Distinct index biopsy results

 T-cell-mediated rejection classified Banff grade > I

 De novo or recurrent severe thrombotic microangiopathy

 Polyoma virus nephropathy

 De novo or recurrent glomerulonephritis