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Table 5 Magnetic resonance imaging and gadolinium contrast injection exclusion criteria

From: A pilot study of the effect of spironolactone therapy on exercise capacity and endothelial dysfunction in pulmonary arterial hypertension: study protocol for a randomized controlled trial

These contraindications include but are not limited to the following devices or conditions:

1.

Implanted cardiac pacemaker or defibrillator

2.

Cochlear Implants

3.

Ocular foreign body (for example, metal shavings)

4.

Embedded shrapnel fragments

5.

Central nervous system aneurysm clips

6.

Implanted neural stimulator

7.

Any implanted device that is incompatible with MRI

8.

Unsatisfactory performance status as judged by the physician such that the participant could not tolerate an MRI scan

9.

Participants requiring monitored sedation for MRI studies

10.

Participants with a condition precluding entry into the scanner (for example, morbid obesity, claustrophobia)

11.

Participants with severe back-pain or motion disorders who will be unable to tolerate supine positioning within the MRI scanner and hold still for the duration of the examination

Exclusion criteria for gadolinium-based MRI studies only:

1.

History of severe allergic reaction to gadolinium contrast agents despite pre-medication with diphenhydramine and prednisone

2.

Chronic kidney disease (estimated glomerular filtration rate of <60 mL/min/1.73 m2 of body surface area)