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Table 2 Predicted cure proportion, log odds and standard error of the log odds by trial type, treatment regimen and duration (average values across the 10,000 simulations)

From: Randomized clinical trials to identify optimal antibiotic treatment duration

Trial type and regimen

Duration in weeks

Average cure proportion

Average log odds of cure

Standard deviation of log odds of cure

Conventional trial design

    

Standard regimen

 

0.900

2.206

0.128

Regimen A

20

0.900

2.207

0.128

Proposed trial design

    

Standard regimen

 

0.900

2.207

0.128

Regimen A

14

0.799

1.390

0.190

Regimen A

16

0.840

1.665

0.146

Regimen A

18

0.874

1.939

0.125

Regimen A

20

0.901

2.214

0.136

Regimen A

22

0.922

2.488

0.174

Regimen A

24

0.939

2.763

0.225

Regimen A

26

0.953

3.037

0.283

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Trials

ISSN: 1745-6215