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Table 2 Predicted cure proportion, log odds and standard error of the log odds by trial type, treatment regimen and duration (average values across the 10,000 simulations)

From: Randomized clinical trials to identify optimal antibiotic treatment duration

Trial type and regimen Duration in weeks Average cure proportion Average log odds of cure Standard deviation of log odds of cure
Conventional trial design     
Standard regimen   0.900 2.206 0.128
Regimen A 20 0.900 2.207 0.128
Proposed trial design     
Standard regimen   0.900 2.207 0.128
Regimen A 14 0.799 1.390 0.190
Regimen A 16 0.840 1.665 0.146
Regimen A 18 0.874 1.939 0.125
Regimen A 20 0.901 2.214 0.136
Regimen A 22 0.922 2.488 0.174
Regimen A 24 0.939 2.763 0.225
Regimen A 26 0.953 3.037 0.283