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Table 2 Cutoff for imbalance in small trials

From: Investigating the relationship between predictability and imbalance in minimisation: a simulation study

Size of trial (number of participants)

Cutoff for imbalance

10

40% (7:3)

20

20% (12:8)

30

10% (17:13)

40

10% (22:18)

≥50

5% (27:23)

  1. Cutoff is given in % (numbers in each of the 2 groups in a 2-treatment trial).