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Table 2 Cutoff for imbalance in small trials

From: Investigating the relationship between predictability and imbalance in minimisation: a simulation study

Size of trial (number of participants) Cutoff for imbalance
10 40% (7:3)
20 20% (12:8)
30 10% (17:13)
40 10% (22:18)
≥50 5% (27:23)
  1. Cutoff is given in % (numbers in each of the 2 groups in a 2-treatment trial).