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Table 1 Possible recommendations from the FEAST charter for the IDMC included

From: When enough is enough: how the decision was made to stop the FEAST trial: data and safety monitoring in an African trial of Fluid Expansion As Supportive Therapy (FEAST) for critically ill children

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No action needed, trial continues

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Early stopping due to clear benefit, or harm of a treatment

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Stopping recruitment within a pre-defined subgroup

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Stopping one or more arms of the trial and recommendation to amend trial

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Proposing or commenting on proposed protocol changes

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Commenting on the Statistical Analysis Plan