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Table 3 Secondary outcome measures

From: Effectiveness of medicines review with web-based pharmaceutical treatment algorithms in reducing potentially inappropriate prescribing in older people in primary care: a cluster randomized trial (OPTI-SCRIPT study protocol)

Secondary outcome Measure
Drug-specific outcomes The absolute number of PIPs per patient of the top five occurring PIP drugs: [11]
Proton pump inhibitor (PPI) for peptic ulcer disease at full therapeutic dosage for >8 weeks
Long-term (>3 months) use of NSAIDs for relief of mild joint pain in osteoarthritis
Long-term (>1 month) use of long-acting benzodiazepines, for example, chlordiazepoxide, flurazepam, nitrazepam, chlorazepate and benzodiazepines with long-acting metabolites for example, diazepam
Any regular duplicate drug class prescription
TCAs with an opiate or calcium channel blocker
Mean number of PIPs per patient of the top five PIP drugs (as above)
Patient-reported outcomes Health status (EQ-5D)
Patients’ Beliefs about Medicine Questionnaire (BMQ)
Well-being Questionnaire (WBQ-12)
Process-of-care measures Number of GP visits (6 months prior to enrolment and at 4 and 12 month follow-up)
Number of hospital admissions (6 months prior to enrolment and at 4 and 12 month follow-up
Process evaluations Decisions made per PIP
Number of times alternatives were prescribed
Reported primary reason for decision made for example, risks outweigh benefits, patient preference, hospital/consultant initiated