Table 1 Screening criteria prior to enrolment

Gestational age and/or weight

Greater than or equal to 35 weeks gestation (or >2.2 kg if gestational age is not available). Infant must be ≤14 days old at the time of first PT.

TcB

Screened daily for the first 7 days of life if in hospital and, when possible, in the community if discharged before 7 days of life or if the patient chooses to come in for screening up to14 days of life. If the TcB is elevated (elevated will be defined as a point 3 mg/dl below that recommended by the AAP for PT in high risk infants and above) at any time during the first 14 days of life, a TSB will be done.

Physical examination (dehydration, oxygen use, ABE, life expectancy, sunburn)

Subjects cannot be dehydrated, sunburned, using oxygen, or have ABE or a life expectancy <24 hours at the time of examination by the physician for enrollment in the treatment phase of the protocol.