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Table 1 Definition and clinical grading of POPF according to the international study group on pancreatic fistula

From: DISCOVER trial– Distal resection of the pancreas with or without coverage of the pancreatic remnant: study protocol of a randomised controlled trial

Definition

Volume of drainage fluid on or after.

Grade A

Clinical condition is good; at most little changes in management are needed. Hospital stay is not delayed; condition is managed by slow removal of drains.

Grade B

Clinical condition is often good; peripancreatic collection may occur. Specific forms of therapy, such as parenteral nutrition and antibiotics in cases of infection, are often needed. Endoscopic stenting of the main pancreatic duct may be necessary for sufficient drainage. Usually, hospital stay is delayed or readmission is required.

Grade C

Clinical condition is poor and stability may be borderline. Major changes in clinical management as intensive care and invasive procedures such as CT-guided drainage, angiography, or re-operations may be needed.