Effectiveness and cost effectiveness of guided online treatment for patients with major depressive disorder on a waiting list for psychotherapy: study protocol of a randomized controlled trial

Table 1 Outcome measures

Questionnaires	Aim	T0 Baseline (pre-test)	T1 Post-test (8 weeks)	T2 Follow-up I (6 months)	T3 Follow-up II (12 months)
Primary outcome
CES-D	Symptoms of depression	X	X	X	X
Secondary outcomes
CIDI (Section E)	Diagnosis of depression	X	X
HADS (Anxiety section)	Symptoms of anxiety	X	X
ISI	Level of insomnia	X	X
EQ-5D	Quality of life	X	X	X	X
Resource use
F2F	Number of face-to-face appointments in MHC				X
TiC-P	General health service uptake and productivity losses	X	X	X	X
Mediator
Mastery scale	Mastery	X	X	X	X
Moderators
Demographic factors	User characteristics	X
NEO-FFI (sections N + C)	Neuroticism and conscientiousness traits	X
CAGE	Alcohol consumption	X
CEQ	Expectancy and treatment	X
AOCEQ	Expectations of the internet intervention	X
CSQ-8	Client satisfaction with treatment		X
AOCSQ	Satisfaction with type of intervention		X

AOCEQ 'Alles Onder Controle’ Expectation Questionnaire, AOCSQ 'Alles Onder Controle’ Satisfaction Questionnaire, CAGE 'Cutting down, Annoyance by criticism, Guilty feeling, and Eye-openers’, CEQ Credibility/Expectancy Questionnaire, CES-D Center for Epidemiological Studies Depression scale, CIDI Composite International Diagnostic Interview, CSQ-8 Client Satisfactory Questionnaire-8, EQ-5D EuroQol 5-Dimensions, F2F face-to-face, ISI Insomnia Severity Index, HADS Hospital Anxiety Depression Scale, MHC mental health center, NEO-FFI NEO-Five Factor Inventory, TiC-P Trimbos and iMTA Questionnaire on Costs Associated with Psychiatric Illness.

ISSN: 1745-6215