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Table 2 Unadjusted and age-adjusted factors for reported consistent gel use

From: Long-term consistent use of a vaginal microbicide gel among HIV-1 sero-discordant couples in a phase III clinical trial (MDP 301) in rural south-west Uganda

Characteristic

N(%)

Consistent gel usersn(%)

uOR (95% CI)

LRTPvalue

Age aOR (95% CI)

LRTPvalue

All participants

544 (100)

369 (67.8)

    

Age group

      

17– 24

92 (16.9)

44 (47.8)

1

<0.01

N/A

 

25–34

237 (43.6)

172 (72.6)

2.9 (1.8–4.8)

   

≥35

215 (39.5)

153 (71.2)

2.7 (1.6–4.5)

   

Religion

      

Christian

472 (86.8)

319 (67.6)

1

0.75

1

0.54

Muslim

72 (13.2)

50 (69.4)

1.1 (0.6–1.9)

 

1.2 (0.7–2.1)

 

Level of education

      

None

81 (14.9)

54 (66.7)

1

0.81

1

0.52

Some education

463 (85.1)

315 (68.0)

1.1 (0.6–1.8)

 

1.2 (0.7–2.0)

 

Employment status

      

Employed

92 (16.9)

55 (59.8)

1

0.07

1

0.11

Unemployed

452 (83.1)

314 (69.5)

1.5 (1.0–2.4)

 

1.5 (0.9–2.4)

 

Family planning use

      

No

227 (41.7)

155 (68.3)

1

0.85

1

0.86

Yes

317 (58.3)

214 (67.5)

0.9 (0.7–1.4)

 

1.0 (0.7–1.4)

 

Condom use

      

No

190 (34.9)

123 (64.7)

1

0.26

1

0.41

Yes

354 (65.1)

246 (69.5)

1.2 (0.9–1.8)

 

1.2 (0.8–1.7)

 

Perceived sexual experience using gel

      

Gel made sex less enjoyable

41 (7.5)

26 (63.4)

1

0.48

1

0.27

Gel left sexual pleasure the same

317 (58.3)

209 (65.9)

1.1 (0.6–2.2)

 

1.2 (0.6–2.4)

 

Gel made sex more enjoyable

186 (34.2)

134 (72.0)

1.5 (0.7–3.2)

 

1.6 (0.8–3.4)

 

Pregnancy status

      

Positive

90 (16.5)

57 (63.3)

1

0.32

1

0.11

Negative

454 (83.5)

312 (68.7)

1.3 (0.8–2.0)

 

1.5 (0.9–2.5)

 

Rooms used for sleeping in at home

      

One

187 (34.4)

111 (59.4)

1

0.02

1

0.03

Two

177 (32.5)

120 (67.8)

1.4 (0.9–2.2)

 

1.2 (0.8–1.9)

 

Three+

180 (33.1)

138 (76.7)

2.2 (1.4–3.5)

 

1.9 (1.2–3.1)

 

Trial arm

      

Placebo

275 (50.6)

183 (66.6)

1

0.52

1

0.58

PRO2000 (0.5%)

269 (49.4)

186 (69.1)

1.1 (0.8–1.6)

 

1.1 (0.8–1.6)

 
  1. uOR, unadjusted odds ratio; CI, confidence interval; LRT, likelihood ratio test; Age aOR, age-adjusted odds ratio.