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Figure 2 | Trials

Figure 2

From: Use of the PiCCO system in critically ill patients with septic shock and acute respiratory distress syndrome: a study protocol for a randomized controlled trial

Figure 2

Algorithm for hemodynamic management in the control arm. If CVP< 8 mmHg, a 500 ml bolus of hydroxyethyl starch 130/0.4 (Voluven®) was infused over 30 min aiming at a CVP of 8 to 12 mmHg. The bolus can be repeated if the target is not reached. If CVP >12 mmHg, furosemide and/or nitroglycerin and/or dobutamine are used at the discretion of the attending physician. If MAP < 60 mmHg, norepinephrine is started at 0.05 μg.kg-1.min-1 with the option to increase at an increment of 0.05 μg.kg-1.min-1. If MAP > 100 mmHg, nitroglycerin is given at the dose range of 0.5 to 3.0 μg.kg-1.min-1. An RBC transfusion is triggered when Hb<7 g.dl-1. ScvO2 is maintained >70%. CVP, central venous pressure; Hb, hemoglobin; RBC, red blood cell; ScvO2, central venous oxygen saturation.

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