Skip to main content

Table 3 Within group and between group differences in the percentages of patients achieving their individual therapeutic targets

From: Effects of a multifaceted intervention on cardiovascular risk factors in high-risk hypertensive patients: the ESCAPE trial, a pragmatic cluster randomized trial in general practice

Target

Group

M0 n/N (%)

M24 n/N (%)

OR (95% CI) within groups

P-value

OR (95% CI) between groups

P-value

Blood pressurea

Intervention

207/900 (23.0)

303/823 (36.8)

2.55 (1.96 to 3.30)

< 0.001

2.03 (1.44 to 2.88)

< 0.001

Usual care

392/923 (42.6)

382/825 (46.3)

1.25 (0.99 to 1.58)

0.060

LDL cholesterolb

Intervention

370/884 (41.9)

458/793 (57.8)

2.65 (2.05 to 3.41)

< 0.001

1.25 (0.88 to 1.78)

0.205

Usual care

395/910 (43.4)

435/778 (55.9)

2.11 (1.65 to 2.71)

< 0.001

No smoking

Intervention

712/905 (78.7)

664/804 (82.6)

3.75 (1.92 to 7.30)

< 0.001

0.81 (0.41 to 1.60)

0.550

Usual care

709/926 (76.6)

659/808 (81.6)

2.98 (1.81 to 4.93)

< 0.001

HbA1cc

Intervention

312/519 (60.1)

275/472 (58.3)

0.81 (0.58 to 1.16)

0.257

0.77 (0.47 to 1.27)

0.310

Usual care

316/512 (61.7)

279/452 (61.7)

1.06 (0.74 to 1.53)

0.747

Low-dose aspirin

Intervention

225/527 (42.7)

318/527 (60.3)

5.55 (3.61 to 8.54)

< 0.001

2.28 (1.27 to -4.09)

0.006

 

Usual care

140/521 (26.9)

179/521 (34.4)

2.43 (1.57 to 3.77)

< 0.001

  
  1. CI, confidence interval; M0, month 0; M24, month 24; OR, odds-ratio.
  2. a ≤ 140/90 mmHg or ≤ 130/80 mmHg for type-2 diabetic patients.
  3. b ≤ 3.36 mmol/l or 2.59 mmol/l for type-2 diabetic patients.
  4. c ≤ 7%.