Table 2 Sample size scenarios
From: Total or Partial Knee Arthroplasty Trial - TOPKAT: study protocol for a randomised controlled trial
Number in each group | Mean difference in OKS | ||||||
|---|---|---|---|---|---|---|---|
2.0 | 3.0 | 4.0 | |||||
Power | SD | 1% sig level | 5% sig level | 1% sig level | 5% sig level | 1% sig level | 5% sig level |
90 | 8.0 | 480 | 340 | 215 | 150 | 120 | 85 |
| Â | 9.0 | 600 | 430 | 270 | 190 | 150 | 110 |
| Â | 10.0 | 740 | 520 | 330 | 235 | 190 | 130 |
80 | 8.0 | 375 | 250 | 170 | 110 | 100 | 60 |
| Â | 9.0 | 470 | 320 | 210 | 140 | 120 | 80 |
| Â | 10.0 | 590 | 390 | 260 | 175 | 150 | 100 |