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Table 1 Characteristics of trials

From: A reinvestigation of recruitment to randomised, controlled, multicenter trials: a review of trials funded by two UK funding agencies

Characteristic 1994 to 2002 2002 to 2008
  N n (%) N n (%)
What type of trial design was used? 122   73  
Parallel   113 (93)   66 (90)
Factorial   6 (5)   4 (5)
Partially randomised patient preference   3 (2)   3 (4)
How many arms were there in the trial? 122   73  
Two   94 (77)   53 (73)
Three   18 (15)   14 (19)
More than three   10 (8)   6 (8)
What clinical area was the trial investigating? 122   73  
Cancer   25 (20)   4 (5)
Mental health (including neurosciences/psychiatry/psychology)   21 (17)   13 (18)
Orthopedics/rheumatology (including back pain)   21 (17)   1 (1)
Obstetrics and gynecology   9 (7)   2 (3)
Primary care   8 (7)   13 (18)
Cardiology   5 (4)   4 (5)
Gastroenterology   5 (4)   0 (0)
Incontinence/urology   5 (4)   3 (4)
HIV/AIDS   5 (4)   4 (5)
Other   18 (15)   29 (40)
In what setting did the trial take place? 122   73  
Hospital   64 (53)   29 (40)
General practice   26 (21)   12 (16)
Mixed   16 (13)   17 (23)
Community   7 (6)   15 (21)
Missing   9 (7)   0 (0)
Were there any recruiting centers outside the UK? 114   73  
No   88 (77)   62 (85)
Yes   25 (22)   11 (15)
Missing   1 (1)   0 (0)
Was a clinical trials unit involved? 114   73  
Yes   89 (78)   31 (42)
No   25 (22)   40 (55)
Missing   0 (0)   2 (3)
Which body funded the trial? 122   73  
UK Medical Research Council (MRC)   73 (64)   41 (56)
UK Health Technology Assessment (HTA)   41 (36)   31 (43)
Both   0 (0)   1 (100)