Figure 1

Consistency of results. Studies are shown as vertices. The graph shows eight experiments across five years with some degree of consistency evident at every phase of research: Both of the in vitro studies, two of the three in vivo, and two of the three phase 1 studies were positive. There is also some inconsistency within in vivo (β ₁) and phase 1 (γ ₂); nevertheless, the accumulating state of evidence is largely positive and the transitions between phases appear relatively smooth.