Figure 1From: Accumulating Evidence and Research Organization (AERO) model: a new tool for representing, analyzing, and planning a translational research program Consistency of results. Studies are shown as vertices. The graph shows eight experiments across five years with some degree of consistency evident at every phase of research: Both of the in vitro studies, two of the three in vivo, and two of the three phase 1 studies were positive. There is also some inconsistency within in vivo (β 1) and phase 1 (γ 2); nevertheless, the accumulating state of evidence is largely positive and the transitions between phases appear relatively smooth.Back to article page